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August 6, 2014

9 Steps to Heal Autoimmune Disease (+ Why it’s Wise to Treat Inflammation)

Editor’s Note: This website is not designed to, and should not be construed to, provide medical advice, professional diagnosis, opinion or treatment to you or any other individual, and is not intended as a substitute for medical or professional care and treatment. For serious. 

What does inflammation mean, how does an autoimmune disease work, and what exactly are doctors doing to treat these conditions? This writer explains, plus steps you can take to heal from autoimmune diseases.

Inflammation is a “hot” topic in medicine. It appears connected to almost every known chronic disease—from heart disease to cancer, diabetes to obesity, autism to dementia, and even depression.

Other inflammatory diseases such as allergies, asthma, arthritis, and autoimmune disease are increasing at dramatic rates. As physicians we are trained to shut off inflammation with aspirin, anti-inflammatory medication such as Advil or Motrin, steroids, and increasingly more powerful immune suppressing medication with serious side effects.

But we are not trained to find and treat the underlying causes of inflammation in chronic disease. Hidden allergens, infections, environmental toxins, an inflammatory diet, and stress are the real causes of these inflammatory conditions.

Autoimmune diseases, specifically, now affect 24 million people and include rheumatoid arthritis, lupus, multiple sclerosis, thyroid disease, inflammatory bowel disease, and more.

These are often addressed by powerful immune suppressing medication and not by addressing the cause. That’s like taking a lot of aspirin while you are standing on a tack. The treatment is not more aspirin or a strong immune suppressant, but removing the tack.

Getting at the Root of the Problem to Treat Inflammation

If you want to cool off inflammation in the body, you must find the source. Treat the fire, not the smoke. In medicine we are mostly taught to diagnose disease by symptoms, not by their underlying cause.

Functional medicine, the emerging 21st century paradigm of systems medicine, teaches us to treat the cause, not only the symptoms, to ask the question why are you sick, not only what disease do you have.

I recently participated in a group discussion with a conventional doctor, a rheumatologist, and patient with an autoimmune disease, and one of my patients who was cured of a complex autoimmune disease by addressing the causes.

The focus of the other doctors, however, was on how to suppress the inflammation with medication, not finding and treating the cause. Functional medicine is a different way of thinking about disease that helps us understand and treat the real causes of inflammation instead of finding clever ways to shut it down. Medicine as it is practiced today is like taking the battery out of a smoke detector while a fire burns down your house!

Autoimmune conditions are connected by one central biochemical process: A runaway immune response also known as systemic inflammation that results in your body attacking its own tissues.

When my patient described how he cured his autoimmune disease by finding and eliminating the causes of inflammation in his diet and environment, it was dismissed as a “spontaneous remission.” In the face of a paradigm-shattering medical case, these doctors were hardly curious and quickly dismissive, describing what was shared as anecdotal.

My patient on that panel, a hard-working 46-year old father of three, was once so inflamed he could barely function. By treating the underlying causes of his inflammation he is now in vibrant good health, enjoying his life with his kids and fully capable of caring for them.

Stories like these (and the many others I have shared in my blogs, books, and on television) are not anecdotes but a giant compass pointing us in the direction we should be looking to find answers to our health problems.

In today’s blog, I will explain what autoimmunity is, how inflammation spirals out of control, describe some of the underlying causes for these fires in the body, and provide you with nine steps to cool the fires of inflammation and overcome conditions that range from allergies to arthritis and more.

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What is Autoimmunity and How Does it Work?

We are facing an epidemic of allergic (60 million people), asthmatic (30 million people), and autoimmune disorders (24 million people). Autoimmune diseases include rheumatoid arthritis, lupus, multiple sclerosis, psoriasis, celiac disease, thyroid disease, and the many other hard-to-classify syndromes in the 21st century.

These are all autoimmune conditions, and at their root they are connected by one central biochemical process: A runaway immune response also known as systemic inflammation that results in your body attacking its own tissues.

Your immune system is your defense against invaders. It is your internal army and has to clearly distinguish friend from foe—to know you from others. Autoimmunity occurs when your immune system gets confused and your own tissues get caught in friendly cross-fire.

Your body is fighting something—an infection, a toxin, an allergen, a food or the stress response—and somehow it redirects its hostile attack on your joints, your brain, your thyroid, your gut, your skin, or sometimes your whole body.

This immune confusion results from what is referred to as molecular mimicry. Conventional approaches don’t have a method for finding the insult causing the problem. Functional medicine provides a map to find out which molecule the cells are mimicking.

Interestingly, autoimmune disorders occur almost exclusively in developed countries. People in poor nations without modern amenities like running water, flush toilets, washing machines, and sterile backyards don’t get these diseases.

If you grew up on a farm with lots of animals, you are also less likely to have any of these inflammatory disorders. Playing in the dirt, being dirty, and being exposed to bugs and infections trains your immune system to recognize what is foreign and what is “you.”

The Health Status of Autoimmune Diseases in America

In this country, autoimmune diseases, when taken all together, are a huge health burden. They are the eighth leading cause of death among women, shortening the average patient’s lifespan by eight years. The annual health care cost for autoimmune diseases is $120 billion a year representing nearly twice the economic health care burden of cancer (about $ 70 billion a year). (i)

Unfortunately, many of the conventional treatments available can make you feel worse. Anti-inflammatory drugs like Advil, steroids, immune suppressants like methotrexate, and the new TNF-alpha blockers like Enbrel or Remicade can lead to intestinal bleeding, kidney failure, depression, psychosis, osteoporosis, muscle loss, and diabetes, not to mention overwhelming infection and cancer.(ii)

When used selectively these drugs can help people get their lives back. But they are not a long-term solution. They shouldn’t be the end of treatment, but a bridge to cool off inflammation while we treat the root cause of the disease.

There is another way to deal with autoimmune conditions. Let me share the same story I told the doctors on that panel.

Recovering from Autoimmunity: Addressing the Causes of Inflammation

My patient Sam ended up on a long misadventure through the medical system before he came to see me. For years he went from doctor to doctor getting all kinds of labels for his problems but no real help in treating them.

This hard-working, once healthy trade professional had suddenly developed a series of inflammatory conditions including chronic sinus and prostate infections. Many doctors gave him many antibiotics for these infections.

Shortly thereafter, he developed severe chest pains and went to the emergency room. While he was there, doctors found swollen lymph nodes and told him he had lymphoma, a form of cancer. For three weeks he lived in despair until the biopsy results came back. It turned out he didn’t have cancer but an autoimmune disease. Which autoimmune disease? The doctors weren’t quite sure…

He had many abnormal blood test results—like low white blood cell and platelet counts, high levels of auto-antibodies of all types (antibodies that attack our own tissues), high immunoglobulins (the foot soldiers of the immune system), and autoimmune thyroid disease. But doctors had a hard time putting their finger on what was wrong. They couldn’t label him.

Meanwhile, Sam developed metabolic syndrome and weight gain (pre-diabetes) as a result of the runaway inflammation in his body.

Here is a quote from one his specialist’s notes:

“Whether he has lupus or Sjogren’s syndrome is a bit unclear. Regardless, he merely needs observation and no therapeutic intervention at this time.”

This unfortunately is all too common. What exactly did they plan to observe, how bad he felt? Or would they just wait for him to get worse before intervening?

That’s when he came to me. Using a functional medicine approach, a new way of thinking about the underlying causes and imbalances in chronic disease, I began by asking Sam some simple questions. Then I went hunting for toxins, allergens, and infections—all common causes of inflammation—and found the real causes of his symptoms.

He had taken so many antibiotics that altered his gut flora or bacteria and promoted yeast overgrowth. Fungus and yeast flourished in his body, growing between his toes, on his toenails, in his crotch, and scalp. He had Helicobacter pylori bacteria in his gut. He had a leaky gut and reacted to many foods, including dairy and gluten. He was exposed to toxins at his job and had high levels of mercury. And he had chronic sinus infections.

So we went to work cleaning house. I treated his yeast with anti-fungals and the H. pylori with antibiotics, got rid of his food allergies, fixed his gut, detoxified him from metals and cleaned up his sinuses.

Then I helped heal his immune system by supporting it with nutrients. I gave him zinc, fish oil, vitamin D, herbs, and probiotics, and put him on a clean, whole-foods, allergen-free, anti-inflammatory diet.

At his next follow-up visit, I asked Sam how he was doing, expecting him to say that he felt a little better. However, his response surprised even me. He said he felt fine.

“What about the fatigue?” I asked.

“I have great energy.”

“What about the bloating and gas?”

“Nope.”

“What about the reflux?”

“Gone.”

“What about your sinuses and chronic phlegm?”

“All clear.”

“What about your memory and concentration problems?”

“All better.”

And he lost 15 pounds.

When his labs came in, they confirmed what he told me—they were all back to normal. His white cells increased and his immune markers calmed way down.

Sam’s results simply reflect the application of a new model of thinking about problems called functional medicine—it’s a way to get to the root of health problems and treat the underlying causes of what ails you instead of suppressing symptoms with medications.

If you have an autoimmune disease, here is what you need to think about and do.

Nine Steps to Treating Inflammation and Autoimmune Disease

1. Check for hidden infections—yeast, viruses, bacteria, Lyme, etc.—with the help of a doctor, and treat them.

2. Check for hidden food allergens with IgG food testing or just try The UltraSimple Diet, which is designed to eliminate most food allergens.

3. Get tested for celiac disease, which is a blood test that any doctor can do.

4. Get checked for heavy metal toxicity. Mercury and other metals can cause autoimmunity.

5. Fix your gut. For details, see my blog on irritable bowel syndrome.

6. Use nutrients such as fish oil, vitamin C, vitamin D, and probiotics to help calm your immune response naturally.

7. Exercise regularly—it’s a natural anti-inflammatory.

8. Practice deep relaxation like yoga, deep breathing, biofeedback, or massage, because stress worsens the immune response.

9. Tell your doctor about Functional Medicine and encourage him or her to get trained—go to functionalmedicine.org for more information and to get a copy of the Textbook for Functional Medicine.

Give these steps a try—and see if you don’t start feeling less inflamed. As I said earlier, the answers are right in front of you. Treat the underlying causes of your illness and you will begin to experience vibrant health once more.

Now I’d like to hear from you…

Have you been diagnosed with an autoimmune disease?

How is your doctor treating you?

Have you been frustrated by the medical advice that you’ve been given?

What steps have you taken to get to the root of the problem, and what have your results been?

Please leave your thoughts by adding a comment below—but remember, we can’t offer personal medical advice online, so be sure to limit your comments to those about taking back our health!

Inflammation

 

References

(i) Nakazawa, D. (2008). The Autoimmune Epidemic. Simon & Schuster. New York.

(ii) Siegel, C.A., Marden, S.M., Persing, S.M., et al. (2009). Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn’s disease: a meta-analysis. Clin Gastroenterol Hepatol. 7(8): 874-81.

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Relephant:

High fiber, low carbohydrate diet dramatically lowers inflammation. 

Natural Remedies to Heal your Thyroid.

How to Reboot & Stop Feeling Like Crap 

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Bonus: Interiews with Dr. Mark Hyman:

 

And The 3-Season Diet—How & Why to Eat Ayurvedically: 

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Author: Dr. Mark Hyman

Editor: Catherine Monkman

Photo: Author’s Own, Pixoto

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miyalaas Jun 4, 2019 4:52am

I’m currently awaiting blood tests and drs appointments while seeking answers to a host of symptoms that point to an autoimmune disorder. I’ve always attempted to trend toward fixing the root cause and not bandaging something with painkillers. But as an adult, I suspect a lot of illnesses when I was younger were already pointing towards autoimmunity. But childhood illnesses happen and it wasn’t something that would have been addressed with more than medication to treat the symptoms. I’m fortunate to have a doc that heard me out and were seeking an answer now. Hopefully my further care involves functional medicine, and even if it doesn’t I can take steps on my own. Grateful these resources exist more widespread than they did when I was a child.

Suey Feb 22, 2019 6:00am

While this is a wonderfully written article on the mechanics of inflammation and disease, I have to disagree with the premise that doctors treat the outcome without regard to treating the causes … at least in my case.
I have multiple sclerosis. My neurologist at the Johns Hopkins Multiple Sclerosis Center is a leader in clinical research focusing on immunopathological and molecular mechanisms associated with neuroimmune disorders.
Those 9 steps outlined in the article for treating inflammation and autoimmune disease? That is not a foreign list to doctors like him. That checklist has all been checked. While I am on pharmaceuticals to control my relapses and development of new lesions, my doctor’s primary focus remains that of monitoring my inflammation markers and triggers and helping me to understand and combat / avoid those triggers.
Fantastic article on autoimmune disease, though.

jtgardner01 Dec 30, 2018 8:01am

I was diagnosed with stage 3c, triple positive breast cancer earlier this year at 31. Ive gone through chemo, surgery, and soon radiation. My response to the chemo was awesome. That could have been luck or that I was supporting myself with a veggie/fruit based vegan diet for the first 3 rounds and then brought meat back in intermittently. I started working with a functional doctor a few weeks ago. One of the red flags she highlighted was that I had taken birth control for about 20 years consecutively. Birth control destroys the metabolities that bind to estrogen so the liver can expel it. Knowing that now, it’s no small wonder I have an estrogen dominance problem. We are still pending a heavy metal toxicity test and food sensitivities test to take a deeper look. To me, all of this should be standard protocol. I am taking two drugs, Herceptin & Perjeta for the HER2 part of my cancer. Those drugs make me breakout in a pretty nasty rash.

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Mark Hyman

Mark Hyman, MD, believes that we all deserve a life of vitality—and that we have the potential to create it for ourselves. That’s why he is dedicated to tackling the root causes of chronic disease by harnessing the power of Functional Medicine to transform healthcare. Dr. Hyman and his team work every day to empower people, organizations, and communities to heal their bodies and minds, and improve our social and economic resilience.
Dr. Hyman is a practicing family physician, a nine-time #1 New York Times bestselling author, and an internationally recognized leader, speaker, educator, and advocate in his field. He is the Director of the Cleveland Clinic Center for Functional Medicine. He is also the founder and medical director of The UltraWellness Center, chairman of the board of the Institute for Functional Medicine, a medical editor of The Huffington Post, and has been a regular medical contributor on many television shows including CBS This Morning, the Today Show, CNN, The View, the Katie Couric show and The Dr. Oz Show.
Dr. Hyman works with individuals and organizations, as well as policy makers and influencers. He has testified before both the White House Commission on Complementary and Alternative Medicine and the Senate Working Group on Health Care Reform on Functional Medicine. He has consulted with the Surgeon General on diabetes prevention, and participated in the 2009 White House Forum on Prevention and Wellness. Senator Tom Harkin of Iowa nominated Dr. Hyman for the President’s Advisory Group on Prevention, Health Promotion, and Integrative and Public Health. In addition, Dr. Hyman has worked with President Clinton, presenting at the Clinton Foundation’s Health MattersAchieving Wellness in Every Generation conference and the Clinton Global Initiative, as well as with the World Economic Forum on global health issues.
Dr. Hyman also works with fellow leaders in his field to help people and communities thrive—with Rick Warren, Dr. Mehmet Oz, and Dr. Daniel Amen,he created The Daniel Plan, a faith-based initiative that helped The Saddleback Church congregation collectively lose 250,000 pounds.  He is an advisor and guest co-host on The Dr. Oz Show and is on the board of Dr. Oz’s HealthCorps, which tackles the obesity epidemic by educating American students about nutrition. With Drs. Dean Ornish and Michael Roizen, Dr. Hyman crafted and helped introduce the Take Back Your Health Act of 2009 to the United States Senate to provide for reimbursement of lifestyle treatment of chronic disease. Dr. Hyman plays a substantial role in a major documentary, produced by Laurie David and Katie Couric, called Fed Up (Atlas Films, September 2014)which addresses childhood obesity. Please join him in helping us all take back our health at his website, follow him on Twitter and on Facebook and Instagram.